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Introducing Quine: An AI research system designed for the complexity of biology.

By Nicolo Fusi, Jonathan M. Carlson

Published 29 Sept 2026

AI brief

Microsoft Research AI introduced Quine, an early-stage research effort to build a multimodal world model of biology that connects insights across biological scales and modalities so scientists can computationally search hypotheses and prioritize them before lab experiments.

Why it matters: It aims to let scientists search a hypothesis space larger than intuition allows and prioritize experiments before they reach the lab.

Written by AI from Microsoft Research AI's published text. Read the original for full details.

From the publisher

Biology doesn't operate in silos, and neither should the AI representation of it. Quine is an early-stage research effort to create a multimodal world model of biology. By connecting insights across biological scales and modalities, Quine helps scientists computationally search a space far larger than intuition allows and prioritize hypotheses before they reach the lab. Experimental results provide important feedback, helping researchers sharpen future research directions.

Research SourcesMultimodal SystemsMicrosoft Research AI
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